 Safe | – | | 出现地点 |
 Safe Code 01 | – | | 出现地点 |
| Safe Code 02 | – | | 出现地点 |
| Scrag Deathgrip Scourge | 19 | Mob | |
| Scrag Gravecrusher | 19 | Mob | |
| Scrag Rustbone Marauder | 19 | Mob | |
| Scrag Tombguard Shredder | 19 | Mob | |
 Second Ingredient Potion | – | | 出现地点 |
 Secret Item | – | | 出现地点 |
 Secret Item Unveiling The Hidden Truth | – | | 出现地点 |
| Seed Hole | – | | |
| Sensor | – | | 出现地点 |
| Sewing Kit | – | | 出现地点 |
 Shiny Lure | – | | 出现地点 |
| Shiny Stone | – | | |
| Shipping Manifests 01 | – | | 出现地点 |
| Shipping Manifests 02 | – | | 出现地点 |
| Shipping Manifests 03 | – | | 出现地点 |
| Shirt Exotic Attire Acquisition | – | | 出现地点 |
 Shoreline Artifact | – | | 出现地点 |
 Shrine Totem Wooden Imp 01 | – | | |
 Shrine Totem Wooden Imp 02 | – | | |
 Shrine Totem Wooden Imp 03 | – | | |
 Shrine Totem Wooden Imp 04 | – | | |
 Shrine Totem Wooden Imp 05 | – | | |
 Shrine Totem Wooden Imp 06 | – | | |
| Signpost Greenville Pointer A | – | NPC | |
| Signpost Greenville Pointer C | – | NPC | |
| Signpost Greenville Pointer E | – | NPC | |
| Signpost Greenville Pointer G | – | NPC | |
| Signpost Pole Greenville Pointer A | – | NPC | |
| Signpost Pole Greenville Pointer B | – | NPC | |
| Signpost Pole Greenville Pointer C1 | – | NPC | |
| Signpost Pole Greenville Pointer C2 | – | NPC | |
| Signpost Pole Greenville Pointer D1 | – | NPC | |
| Signpost Pole Greenville Pointer D2 | – | NPC | |
| Signpost Pole Greenville Pointer D3 | – | NPC | |
| Slate Ghetto Body Kit Hub Door 02 | – | | |
| Slippery Passage Prisoner 01 | – | | 出现地点 |
| Slippery Passage Prisoner 02 | – | | 出现地点 |
| Slippery Passage Prisoner 03 | – | | 出现地点 |
| Slippery Passage Prisoner 04 | – | | 出现地点 |
 SLPY | 39 | MobGuard | 出现地点 |
| SLPY-05 | – | MobGuard | 出现地点 |
 Smoker Timmy | – | | 出现地点 |
 SNZY | 39 | MobGuard | 出现地点 |
| SNZY-04 | – | MobGuard | 出现地点 |
| Soldier 03 Fragment 01 | – | | 出现地点 |
| Soldier 03 Fragment 03 | – | | 出现地点 |
 Soldier 03 Note 1 | – | | 出现地点 |