NPCs & creatures
Mobs, bosses, NPCs, vendors, chests
| Unit | Level | Tags | Has |
|---|---|---|---|
 Intoxicating Flower | — | ||
| Io | — | NPCQuest | |
| Iron Rivets | — | spawns | |
| Isaac | — | NPC | |
| Isaac | — | NPC | |
| Isaac | — | NPC | |
| Isaac Active Object Inherit1 | — | ||
| Isaac Active Object Inherit2 | — | ||
| Isaac Active Object Inherit3 | — | ||
 Isopropyl Alcohol | — | spawns | |
 Ivie Clarkson | — | NPCVendorQuest | vendorspawns |
 J'brahah | — | NPCQuest | |
| Jack | — | Quest | |
| Jacob | — | NPCQuest | |
| Jade Falcon | — | ||
| Jade Quickshade | — | NPC | vendorspawns |
| Jahri Bubbler | — | spawns | |
| Jahri Roots | — | NPCQuest | vendorspawns |
| Jasper Wilde | — | NPCQuest | |
| Jax | — | NPC | vendor |
| Jayla | — | NPCQuest | |
| Jeffery Schaefer | — | NPC | vendor |
| Jennifer Davyna | — | NPC | vendorspawns |
| Jennifer Davyna | — | NPC | vendorspawns |
| Jerry | — | NPC | |
| Jett Stringer | — | NPC | vendorspawns |
| Joe | — | NPCQuest | |
| Jogvan | — | NPC | |
| Jose | — | NPCQuest | |
| Journeyman | — | NPC | |
| Jude Firth | — | NPC | vendor |
| Jug | — | ||
| Jug | — | ||
| Jug | — | ||
| Jug | — | ||
| Jug | — | ||
| Jug | — | ||
| Jug | — | ||
| Jug | — | ||
| Jug | — | ||
| Jug | — | ||
| Jug | — | ||
| Junior archaeologist | — | NPC | |
 Junior Post Officer | — | NPCQuest | |
| Junkhead | — | NPCQuest | |
 Kaelyn "Blaze" Ainsley | — | NPCVendor | vendorspawns |
 Kain | — | Vendor | |
| Kainos | — | NPCQuest | |
| Kedwick | — | NPC | |
| Keeper of Souls | — | Hero |