| Signpost Greenville Pointer A | – | NPC | |
| Signpost Greenville Pointer C | – | NPC | |
| Signpost Greenville Pointer E | – | NPC | |
| Signpost Greenville Pointer G | – | NPC | |
| Signpost Pole Greenville Pointer A | – | NPC | |
| Signpost Pole Greenville Pointer B | – | NPC | |
| Signpost Pole Greenville Pointer C1 | – | NPC | |
| Signpost Pole Greenville Pointer C2 | – | NPC | |
| Signpost Pole Greenville Pointer D1 | – | NPC | |
| Signpost Pole Greenville Pointer D2 | – | NPC | |
| Signpost Pole Greenville Pointer D3 | – | NPC | |
| Silas Thorne | – | NPCQuest | VendorSpawns |
| Silas Thorne | – | NPCQuest | VendorSpawns |
| Silas Whitlock | – | NPCQuest | VendorSpawns |
| Sirena Hexblade | – | NPCQuest | VendorSpawns |
 Skalberath | – | NPCQuest | Spawns |
| Skeleton | – | Chest | |
| Skeleton Archer | 19 | Mob | |
| Skeleton Healer | 19 | Mob | |
| Skeleton Warrior | 19 | Mob | |
| Skip Stones | – | NPC | Vendor |
| Skrizzik | – | NPC | Vendor |
| Slate Ghetto Body Kit Hub Door 02 | – | | |
| Slayer occultist | 14 | Mob | |
| Slayer occultist | 14 | Mob | |
| Slayer occultist | 14 | Mob | |
| Slayer occultist | 14 | Mob | |
| Slayer occultist | 14 | Mob | |
| Slayer occultist | 14 | Mob | |
| Slayer occultist | 14 | Mob | |
| Slayer occultist | 14 | Mob | |
| Slayer occultist | 14 | Mob | |
| Slayer occultist | 14 | Mob | |
| Slayer occultist | 14 | Mob | |
| Slayer occultist | 14 | Mob | |
| Slayer occultist | 14 | Mob | |
| Slayer occultist | 14 | Mob | |
| Slayer occultist | 14 | Mob | |
| Slayer occultist | 14 | Mob | |
| Slayer occultist | 19 | Mob | |
| Slayer occultist | 19 | Mob | |
| Slayer occultist | 19 | Mob | |
| Slayer occultist | 19 | Mob | |
| Slick Shady | – | NPCQuest | VendorSpawns |
| Slick Shady | – | NPCQuest | VendorSpawns |
| Slippery Passage Prisoner 01 | – | | Spawns |
| Slippery Passage Prisoner 02 | – | | Spawns |
| Slippery Passage Prisoner 03 | – | | Spawns |
| Slippery Passage Prisoner 04 | – | | Spawns |
 SLPY | 39 | MobGuard | Spawns |